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Formulated by physicians from
Harvard, Cornell, MIT and Bastyr

Cardiovascular Support

NattoPine contains the highest dose combination of nattokinase and a pine bark extract to support heart, blood pressure and blood vessel health by promoting healthy blood flow, circulation and healthy blood clotting. NattoPine provides 3650 fibrinolytic units (182.5 mg) nattokinase and 300 mg pine bark extract per serving.

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Highest dose combination of nattokinase and pine bark extract
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Highest dose combination of nattokinase and pine bark extract
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182.5 mg nattokinase (3650 fibrinolytic units) and 300 mg pine bark extract per serving
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182.5 mg nattokinase (3650 fibrinolytic units) and 300 mg pine bark extract per serving
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Supports healthy blood clotting, blood pressure and circulation
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Supports healthy blood clotting, blood pressure and circulation

NattoPine Results

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How NattoPine Compares

*Footnotes

**Nattokinase is an extract from a Natto, a Japanese food from fermented soybeans. Nattokinase supports healthy blood clotting within normal levels and promotes healthy circulation and blood pressure.*

FU (fibrinolytic units) indicates the blood-clot dissolving strength of nattokinase. 

††Pine bark extract contains powerful antioxidants to support heart and blood vessel health.* 

*These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure, or prevent any disease.

NattoPine Formula Citations:
Cui Y, Xie H, Wang J. Potential biomedical properties of Pinus massoniana bark extract. Phytother Res. 2005;19(1):34-38.
Li YY, Feng J, Zhang XL, Cui YY. Pine bark extracts: nutraceutical, pharmacological, and toxicological evaluation. J Pharmacol Exp Ther. 2015;353(1):9-16.
Kim JY, Gum SN, Paik JK, et al. Effects of nattokinase on blood pressure: a randomized, controlled trial. Hypertens Res. 2008;31(8):1583-1588.
Kurosawa Y, Nirengi S, Homma T, et al. A single-dose of oral nattokinase potentiates thrombolysis and anti-coagulation profiles. Sci Rep. 2015;5:11601.
Weng Y, Yao J, Sparks S, Wang KY. Nattokinase. Int J Mol Sci. 2017;18(3):523.

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Research Citations

Nattokinase and Pine Bark Extract Citations

Cui Y, Xie H, Wang J. Potential biomedical properties of Pinus massoniana bark extract. Phytother Res. 2005;19(1):34-38.

Li YY, Feng J, Zhang XL, Cui YY. Pine bark extracts: nutraceutical, pharmacological, and toxicological evaluation. J Pharmacol Exp Ther. 2015;353(1):9-16.

Kim JY, Gum SN, Paik JK, et al. Effects of nattokinase on blood pressure: a randomized, controlled trial. Hypertens Res. 2008;31(8):1583-1588.

Kurosawa Y, Nirengi S, Homma T, et al. A single-dose of oral nattokinase potentiates thrombolysis and anti-coagulation profiles. Sci Rep. 2015;5:11601.

Weng Y, Yao J, Sparks S, Wang KY. Nattokinase. Int J Mol Sci. 2017;18(3):523.